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Omee Capsule 20’s

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Description

OMEPRAZOLE belongs to the class of drugs known as Proton pump inhibitor (PPIs) which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcer, and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour).

OMEPRAZOLE helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. OMEPRAZOLE prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

OMEPRAZOLE can be prescribed to the adults and children aged 12 years and over. It is better to take OMEPRAZOLE an hour before a meal. OMEPRAZOLE should be swallowed whole with a glass of water. Do not chew, crush, or break it. Besides this, OMEPRAZOLE is also available in liquid form for those who cannot swallow tablets or capsules. Do not take OMEPRAZOLE for more than 4 weeks of duration without consulting the doctor. You can increase the efficacy of OMEPRAZOLE by taking a small meal or snacks frequently. Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated beverages, acidic foods like citrus fruits/vegetables (tomatoes).

An adult taking OMEPRAZOLE might have common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. Respiratory system problems can be reported in some children (more than 1 year) using OMEPRAZOLE. These side effects are temporary and may get resolve after some time however if this side persists contact the doctor.

OMEPRAZOLE should not be given to the patient suffering from Clostridium difficile associated diarrhoea. OMEPRAZOLE is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, allergic to OMEPRAZOLE, or will have an endoscopy in the future. Ask your doctor if you should stop taking OMEPRAZOLE a few weeks before your endoscopy as it may hide some of the problems that would be spotted during an endoscopy. Prolonged use of OMEPRAZOLE may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine due to loss of magnesium. Avoid using OMEPRAZOLE with St John’s Wort (plant-based antidepressant), rifampin (antibiotic) and methotrexate (anti-cancer and anti-arthritis medicine) due to the severe drug interaction.

Uses of OMEPRAZOLE

Stomach ulcers, Acid reflux (Gastroesophageal Reflux Disease – GERD), Hyperacidity, Zollinger Ellison syndrome

Medicinal Benefits

OMEPRAZOLE is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome, stomach ulcers.  OMEPRAZOLE works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mother, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups. It should not be given to the children less than 1 year of age as no clinical studies has been done.

Directions for Use

It is better to take OMEPRAZOLE an hour before a meal. OMEPRAZOLE should be swallowed whole with a glass of water. Do not chew, crush, or break it. Besides this, OMEPRAZOLE is also available in liquid form for those who cannot swallow tablets or capsules. Do not take OMEPRAZOLE for more than 4 weeks of duration without consulting the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of OMEPRAZOLE

An adult taking OMEPRAZOLE might have common side effects like stomach pain, gas formation (flatulence), nausea, vomiting, diarrhoea, and headache. Respiratory system problems can be reported in some children (more than 1 year) using OMEPRAZOLE. These side effects are temporary and may get resolve after some time however if this side persists contact the doctor.

In-Depth Precautions and Warning

Drug Warnings

OMEPRAZOLE should not be given to the patient suffering from Clostridium difficile associated diarrhoea. OMEPRAZOLE is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, allergic to OMEPRAZOLE, or will have an endoscopy in the future. Ask your doctor if you should stop taking OMEPRAZOLE a few weeks before your endoscopy as it may hide some of the problems that would be spotted during an endoscopy. Prolonged use of OMEPRAZOLE may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine due to loss of magnesium. Avoid using OMEPRAZOLE with St John’s Wort (plant-based antidepressant), rifampin (antibiotic) and methotrexate (anti-cancer and anti-arthritis medicine) due to the severe drug interaction.

Drug Interactions

Drug-Drug Interaction: OMEPRAZOLE may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.

Drug-Food Interaction: OMEPRAZOLE interact with St John’s wort plant that is used as an anti-depressant. This plant may affect the working of OMEPRAZOLE. So avoid its intake with OMEPRAZOLE.

Drug-Disease Interaction: OMEPRAZOLE should be not given in patients with C. difficile induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), low magnesium (hypomagnesemia).

Safety Advice

  • Safety Warning

    Alcohol

    Drinking alcohol with OMEPRAZOLE may cause dehydration and elevate the level of stomach acid thereby decreasing its efficiency. So try to avoid, limit alcohol or contact doctor before intake of OMEPRAZOLE.

  • Safety Warning

    Pregnancy

    It is not known whether OMEPRAZOLE affects the baby or not. So, contact a doctor before intake of OMEPRAZOLE. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

  • Safety Warning

    Breast Feeding

    OMEPRAZOLE passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of OMEPRAZOLE. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

  • Safety Warning

    Driving

    In some cases, OMEPRAZOLE may cause dizziness, sleepy, or blur vision. If you observe these symptoms do not drive or operate heavy machinery until you feel better.

  • Safety Warning

    Liver

    OMEPRAZOLE should be taken with precaution in patients with liver disease.

  • Safety Warning

    Kidney

    Patients with kidney disease should consult a doctor before taking OMEPRAZOLE.

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
  • Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
  • Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Patients Concern

Disease/Condition Glossary

Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine) (the duodenum). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumour of the pancreas causes excessive acid production leading to peptic ulcers.

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